PPI for Cell Wall Synthesis Related Proteins in A.thaliana



The most reliable 42 candidates with additional evidences except for PPI
Acc number Name in TAIR Pfam domain Subnetworks/clusters related to it Interacting partners
AT3G09440HSC70-3 (heat shock cognate 70 kDa protein 3) HSP70discrete_2Partner IDs
AT4G35450AKR2 (Ankyrin repeat-containing protein 2) 2 Ankcluster_2Partner IDs
AT2G16950Protein transporter4 HEAT; IBN_Ndiscrete_5Partner IDs
AT2G01320ABC transporter family proteinABC_tran; ABC2_memberanecluster_4Partner IDs
AT1G03000PEX6(Peroxin 6); ATPase2 AAAdiscrete_2Partner IDs
AT1G54080 UBP1A (Oligouridylate-binding protein 1A 3 RRM_1cluster_8Partner IDs
AT2G47470UNE5 (Unfertillized embryo SAC 5); protein disulfide isomerase2 Thioredoxincluster_7Partner IDs
AT4G34460AGB1 (GTP Binding protein beta 1)5 WD40discrete_2Partner IDs
AT1G17070D111/G-patch domain-containing proteinG-patch; TFP11discrete_8Partner IDs
AT1G04510transducin / WD-40 repeat family protein3 WD40; Prp19cluster_10Partner IDs
AT1G72340Eukaryotic translation initiation factor 2B (eIF-2B) family protein IF-2Bdiscrete_5Partner IDs
AT3G09550Ankyrin repeat family protein3 Ankcluster_9Partner IDs
AT4G26840SUM1 (Small ubiquitin-like modifier 1)ubiquitincluster_4Partner IDs
AT1G01960EDA10 (embryo sac development arrest 10); guanyl-nucleotide exchange factorDUF1981; Sec7discrete_3Partner IDs
AT1G24280G6PD3 (Glucose-6-phosphate dehydrogenase 3)G6PD_N; G6PD_Ccluster_7Partner IDs
AT3G22845Emp24/gp25L/p24 protein-relatedEMP24_GP25Ldiscrete_3Partner IDs
AT1G63210RNA binding / hydrolase, acting on ester bonds / protein binding / transcription elongation regulatorNAcluster_2Partner IDs
AT5G24318Catalytic/ cation binding / hydrolase, hydrolyzing O-glycosyl compoundsGlyco_hydro_17; X8discrete_5Partner IDs
AT3G21340Leucine-rich repeat protein kinase, putativePkinasecluster_1Partner IDs
AT5G22060ATJ2 (Arabidopsis thaliana DnaJ homologue 2)DnaJ_CXXCXGXG; DnaJ; DnaJ_Cdiscrete_3Partner IDs
AT5G54750TRAPP (Transport protein particle) component Bet3, putativeTRAPP_Bet3discrete_3Partner IDs
AT4G03560ATTPC1 (Two-pore channel 1); calcium channel/ voltage-gated calcium channel2 Ion_trans; efhanddiscrete_3Partner IDs
AT1G25460Oxidoreductase family proteinEpimerasecluster_7Partner IDs
AT5G19680Leucine-rich repeat family proteinNAcluster_7Partner IDs
AT3G01090AKIN10 (Arabidopsis SNF1 kinase homolog 10) Pkinase; UBA; KA1discrete_3Partner IDs
AT3G12110Actin 11Actincluster_5Partner IDs
AT5G59210Myosin heavy chain-relatedNAcluster_9Partner IDs
AT5G41700UBC8 (Ubiquitin conjugating enzyme 8) UQ_condiscrete_3Partner IDs
AT3G59510Leucine-rich repeat family proteinLRRNT_2cluster_2Partner IDs
AT2G43770Transducin / WD-40 repeat family protein7 WD40cluster_2Partner IDs
AT5G24940PP2C (Protein phosphatase 2C), putative PP2Cdiscrete_3Partner IDs
AT4G29880Protein bindingNAcluster_7Partner IDs
AT3G18430Calcium-binding EF hand family proteinefhanddiscrete_3Partner IDs
AT3G19980ATFYPP3 (Serine/threonine protein phosphatase)Metallophosdiscrete_5Partner IDs
AT5G25760PEX4 (Peroxin 4); ubiquitin-protein ligaseUQ_condiscrete_3Partner IDs
AT5G17770ATCBR (NADH:Cytochrome B5 reductase 1)NAD_binding_1; FAD_binding_6discrete_3Partner IDs
AT3G08980Signal peptidase I family proteinPeptidase_S24discrete_3Partner IDs
AT1G15130Hydroxyproline-rich glycoprotein family proteinBRO1discrete_3Partner IDs
AT4G36960RRM (RNA recognition motif)-containing protein3 RRM_1cluster_2Partner IDs
AT1G68980PPR (pentatricopeptide) repeat-containing protein2 PPRcommon_interaction_partnerPartner IDs
AT3G55830EPC1 (Ectopically Parting Cells); transferase, transferring glycosyl groupsEXTL23node_15|common_interaction_partnerPartner IDs
AT5G41180Leucine-rich repeat protein kinase, putativeLRRNT_2; Pkinase_Tyrcommon_interaction_partnerPartner IDs

The remaining 50 candidates
Acc number Name in TAIR Pfam domain Subnetworks/clusters related to it Interacting partners
AT1G06530Myosin heavy chain-relatedNAcluster_7Partner IDs
AT1G03457RNA-binding protein, putative3 RRM_1cluster_8Partner IDs
AT1G17370UBP1B(Oligouridylate binding protein 1B)3 RRM_1cluster_2Partner IDs
AT2G19430Transducin / WD-40 repeat family protein2 WD40cluster_1Partner IDs
AT1G62720Unknown9 PPRcluster_8Partner_IDs
AT1G71420PPR (pentatricopeptide) repeat-containing protein3 PPRdiscrete_1Partner IDs
AT2G26300GP Alpha 1 (G protein alpha subunit 1); GTP binding / GTPase/ channel regulator/ signal transducerG-alphadiscrete_2Partner IDs
AT3G04220TIR-NBS-LRR class (disease resistance protein), putativeNB-ARC; TIR; LRR_3discrete_1Partner IDs
AT1G22280PP2C (protein phosphatase 2C), putative PP2Ccluster_1Partner IDs
AT1G02990 Zinc ion binding NAcluster_1Partner_IDs
AT1G01910Anion-transporting ATPase, putativeArsA_ATPasecluster_6Partner IDs
AT1G63230PPR (pentatricopeptide) repeat-containing protein7 PPRcluster_7Partner IDs
AT1G34370 STOP1 (sensitive to proton rhizotoxicity 1); nucleic acid binding / transcription factor/ zinc ion bindingzf-C2H2cluster_2Partner IDs
AT1G49600ATRBP47A (Arabidopsis thaliana RNA-binding protein 47A); RNA binding3 RRM_1discrete_4Partner IDs
AT3G01750Ankyrin repeat family protein2 Ankdiscrete_7Partner IDs
AT3G50670 U1-70K (U1 small unclear ribonucleoprotein-70K); RNA / nucleotide binding RRM_1cluster_6Partner IDs
AT4G30890 UBP24 (Ubiquitin-specific protease 24); ubiquitin thiolesterase/ ubiquitin-specific proteaseUCHdiscrete_3Partner IDs
AT1G19120snZRNP (small nuclear ribonucleoprotein), putativeLSMdiscrete_3Partner IDs
AT5G07840Ankyrin repeat family protein2 Ankcluster_1Partner IDs
AT3G16130ROPGEF13 (Kinase partner protein-like); Rho guanyl-nucleotide exchange factorDUF315cluster_1Partner IDs
AT3G14600RPL18ac (60S ribosomal protein L18A)Ribosomal_L18aediscrete_3Partner IDs
AT5G55300TOP1BETA (DNA topoisomerase 1 beta); DNA topoisomerase type ITopoisom_I_N; Topoisom_Idiscrete_3Partner IDs
AT1G47500TRBP47C (RNA-binding protein 47C); RNA binding3 RRM_1cluster_9Partner IDs
AT3G16710PPR (pentatricopeptide) repeat-containing protein11 PPRcluster_9Partner IDs
AT5G20570RBX1 (Ring-Box 1)NAcluster_6Partner IDs
AT3G49470 NACA2 (Nascent polypeptide-associated complex subunit alpha-like protein 2)NACcluster_1Partner IDs
AT2G43810Small nuclear ribonucleoprotein F, putativeLSMdiscrete_3Partner IDs
AT1G08820VAP27-2 (Vamp/Synaptobrevin-associated protein 27-2); structural moleculeMotile_Spermdiscrete_3Partner IDs
AT5G13270PPR (pentatricopeptide) repeat-containing protein4 PPRdiscrete_1Partner IDs
AT3G22110PAC1 (20S proteasome alpha subunit C1); endopeptidase/ peptidase/ threonine-type endopeptidaseProteasomediscrete_3Partner IDs
AT3G06460GNS1/SUR4 membrane family proteinNAdiscrete_3Partner IDs
AT2G18290APC10 (anaphase-promoting complex, subunit 10) familyAPC10discrete_3Partner IDs
AT4G37940AGL21 (Agamous-like 21); transcription factorK-box; SRF-TFdiscrete_3Partner IDs
AT3G22470PPR (pentatricopeptide) repeat-containing protein14 PPRdiscrete_6Partner IDs
AT2G38960AERO2 (Arabidopsis endoplasmic reticulum oxidoreductins 2)ERO1discrete_3Partner IDs
AT5G23670LCB2 (Serine palmitoyltransferase long chain base subunit gene); serine C-palmitoyltransferaseAminotran_1_2discrete_3Partner IDs
AT4G20990ACA4 (Alpha carbonic anhydrase 4); carbonate dehydratase/ zinc ion bindingCarb_anhydrasecluster_1Partner IDs
AT5G60870RCC1 (Regulator of chromosome condensation) family protein3 RCC1discrete_4Partner IDs
AT1G29880Glycyl-tRNA synthetase / Glycine--tRNA ligasetRNA-synt_2b; WHEP-TRS; HGTP_anticodondiscrete_3Partner IDs
AT4G38630 RPN10 (Regulatory particle non-ATPase 10); peptide receptorUIMdiscrete_3Partner IDs
AT5G08710RCC1 (Regulator of chromosome condensation (RCC1) family protein / UVB-resistance protein-related3 RCC1cluster_9Partner IDs
AT2G32160Unknown proteinNAcluster_6Partner_IDs
AT4G11080High mobility group (HMG1/2) family protein3 HMG_boxdiscrete_3Partner IDs
AT4G34110PAB2 (Poly(A) binding 2); RNA binding / translation initiation factor2 RRM_1; PABPcluster_8Partner IDs
AT2G40700DEAD/DEAH box helicase, putative (RH17)Helicase_C; DEADdiscrete_3Partner IDs
AT1G48360HydrolaseHIRANcommon_interaction_partnerPartner IDs
AT1G55680WD-40 repeat family proteinWD40common_interaction_partnerPartner IDs
AT1G67820PP2C (Protein phosphatase 2C), putativePP2Ccommon_interaction_partnerPartner IDs
AT3G01540DRH1 (DEAD box RNA helicase 1)DEAD; WW; Helicase_Ccommon_interaction_partnerPartner IDs
AT3G48400DC1 domain-containing protein2 C1_1; 6 C1_3; 2 C1_2common_interaction_partnerPartner IDs


In each graph, the yellow nodes represent the known CWSR proteins and the blue ones for the uncharacterized candidate CWSR proteins. In the graph for candidate CWSR proteins identified by sharing exactly the same interacting partners with some known CWSR proteins, the nodes in purple are the common interacting partners between candidate CWSR proteins and known CWSR proteins.

Note that: perhaps not all of the candidates specifically play a role in cell wall synthesis and they may have other biological functions. Besides, though it seems that some candidates have house-keeping function from their names, they are likely to important to cell wall synthesis, such as Golgi transporters.

Abbreviations: GH, glycosyl hydrolase family; PE, pectinesterase family; PG, polygalacturonase (pectinase); SUD, soluble UDP-D -glucuronic acid decarboxylase gene; UGE, UDP-glucose 4-epimerase/UDP-galactose 4-epimerase; UXE, UDP-D-xylose 4-epimerase. All graphs were drawn using the Cytoscape software (Shannon et al., 2003; Cline et al., 2007).