Wen Zhou, Ph.D.

 

Postdoctoral fellow
Computational Systems Biology Laboratory

Department of Biochemistry and Molecular Biology &

Institute of Bioinformatics 

University of Georgia

 

Email: wzhou@csbl.bmb.uga.edu

Tel: (706) 542-8968; Fax: (706) 542-9751

Mailing address:

A110, Life Science Building
120 East Green St.

Athens, Georgia 30602

 

Research Interests

Computational systems biology and bioinformatics: reaction/pathway networks inference, modeling and analysis. One of the particular applications focuses on the biofuel production through biological conversion of biomass, which is supported through the DOE funded BioEnergy Science Center (BESC).

 

Education

Postdoc, Dept. of Biochemistry and Molecular Biology, Nov. 2006 -

University of Georgia, Athens, GA

Advisor: GRA Eminent Scholar and Regents Prof. Ying Xu

 

Ph.D., Dept. of Chemical and Biomolecular Eng., Jan. 2001 - Sep. 2006

University of California, Los Angeles, CA

Advisor: Dr. Vasilios Manousiouthakis

 

B.E., Dept. of Chemical and Biomolecular Eng., Sep. 1993 - Jun. 1998

Tsinghua University, Beijing, China

Advisor: Dr. Shanying Hu

 

Journal Publications

  1. Zhou, W.; Xu, Y. and Schuttler, HB. Cellulose hydrolysis in evolving substrate morphologies III: time scale analysis. (submitted)
  2. Liu B*, Zhou W*, Li G, Xu Y. (* equal contribution) Identification of cis-regulatory elements in prokaryotes through an integrative approach. (to be submitted)  
  3. Zhou, W.; Hao, Z.; Xu, Y. and Schuttler, HB. Cellulose hydrolysis in evolving substrate morphologies II: numerical results and analysis. Biotechnology and Bioengineering. 104, 275-289, 2009.
  4. Zhou, W.; Schuttler, HB.; Hao, Z. and Xu, Y. Cellulose hydrolysis in evolving substrate morphologies I: a general modeling formalism. Biotechnology and Bioengineering. 104, 261-274, 2009.
  5. Zhou, W. and Manousiouthakis, V. I. Automating the AR Construction for Non-isothermal Reactor Networks. Computers and Chemical Engineering. 33, 176-180, 2009.
  6. Zhou, W. and Manousiouthakis, V. I. Global capital/total annualized cost minimization of reactor network. Industrial and Engineering Chemistry Research. 47, 3771-3782, 2008.
  7. Zhou, W. and Manousiouthakis, V. I. On dimensionality of Attainable Region construction for isothermal reactor networks. Computers and Chemical Engineering. 32, 439-450, 2008.
  8. Zhou, W. and Manousiouthakis, V. I. Variable density fluid reactor network synthesis - construction of the Attainable Region through the IDEAS approach. Chemical Engineering Journal. 129, 91-103, 2007.
  9. Zhou, W. and Manousiouthakis, V. I. Pollution prevention through reactor network synthesis: the IDEAS approach. International Journal of Environment and Pollution. 29, 206-231, 2007.
  10. Zhou, W. and Manousiouthakis, V. I. Non-ideal reactor network synthesis through IDEAS: Attainable Region construction. Chemical Engineering Science, 61, 6936-6945, 2006.
  11. Zhou, W. and Hu, S. Y. A simulation, on-line parameter estimation and optimization system for fuel-type crude vacuum distillation columns: I) simulation. Petrochemical Industry Technology (in Chinese), Vol. 20 (3), 1999.
  12. Zhou, W. and Hu, S. Y. A simulation, on-line parameter estimation and optimization system for fuel-type crude vacuum distillation columns: II) on-line parameter estimation and optimization. Petrochemical Industry Technology (in Chinese), Vol. 20 (4), 1999.

Conference Presentations/Proceedings

  1. Zhou W, Liu B, Xu Y. An Integrative Pipeline for Detecting Bacterial Regulation Networks and Its Application to C. Thermocellum Cellulosome Production. Jun. 2009, BESC third science retreat, Asheville NC.
  2. Zhou W, Hao Z, Xu Y, Schuttler HB. Cellulose Hydrolysis in Evolving Substrate Morphologies. Dec. 2008, BESC second science retreat, Chattanooga, TN.
  3. Zhou W, Xu Y. Investigation on microbial pathways. Mar. 2007, 2nd Annual Computational and Systems Biology Symposium, Athens, GA.
  4. Zhou W, Manousiouthakis VI. Non-isothermal reactor network synthesis through IDEAS. Nov. 2005, AICHE 2005 Annual Meeting, Cincinnati, OH.
  5. Zhou W, Manousiouthakis VI. Multiphase reaction network synthesis by the IDEAS approach. Nov. 2005, AICHE 2005 Annual Meeting, Cincinnati, OH.
  6. Zhou W, Manousiouthakis VI. On dimensionality of the AR construction. Nov. 2005, AICHE 2005 Annual Meeting, Cincinnati, OH.
  7. Zhou W, Davis BJ, Manousiouthakis VI. High dimension AR numerical construction. Nov. 2004, AICHE 2004 Annual Meeting, Austin, TX.
  8. Zhou W, Manousiouthakis VI. Non-isothermal reaction network synthesis. Nov. 2004, AICHE 2004 Annual Meeting, Austin, TX.
  9. Zhou W, Manousiouthakis VI. Globally optimal synthesis of non-constant density reactor networks using the IDEAS approach. Nov. 2003, AICHE 2003 Annual Meeting, San Francisco, CA.
  10. Zhou W, Manousiouthakis VI. Capital Cost Minimization for Process Networks Using the IDEAS Approach. Nov. 2002, AICHE 2002 Annual Meeting, Indianapolis, IN.

Invited talks

Modeling of Cellulose Hydrolysis Considering Substrate Morphologies. Jun. 2009, BESC (BioEnergy Science Center) third science retreat, Asheville NC

 

Detecting the effect of cellulosic substrate morphologies on cellulose hydrolysis: a computational perspective. Apr. 2009, Institute Of Bioinformatics at University of Georgia, Athens, GA

 

Biofuel Industry: Current Status, Future and Challenges. Jan. 2009, Department of Chemical Engineering at University of South Florida, Tampa, FL

 

Cellulose Hydrolysis in Evolving Substrate Morphologies. Jan. 2009, Department of Chemical Engineering at University of South Florida, Tampa, FL

 

 

Modified 10/2009