Education
- Ph.D. [Aug. 2007 ~ Summer 2012]
Institute of Bioinformatics, University of Georgia
(research focus: cellulosic biofuel and cancer informatics) - M.S. [Jun. 2002]
Institute of Cell and Molecular Biology, Taipei Medical University
(research focus: Vaccinia virus entry) - B.S. [Jun. 2000]
School of Medical Technology, Chung Shan Medical University
(research focus: gram-negative bacterial protein secretion)
Professional Experience
- Research Assistant [Aug. 2007 ~ Aug. 2012]
Computational Systems Biology Laboratory, UGA - Research Intern [May 2011 ~ Aug. 2011]
Eli Lilly, Indianapolis
(research focus: Functional cancer genomics) - Research Assistant [Sep. 2000 ~ Apr. 2007]
Institute of Molecular Biology & Institute of Information Science, Academia Sinica
(research focus: Vaccinia virus entry and biomedical text mining) - Medical Technologist Trainee [Sep. 1999 ~ Feb. 2000]
Jen-Ai Hospital, Taiwan
Publications [pubmed]
Papers
- "Genome-wide Survey of Recurrent HBV Integration in Hepatocellular Carcinoma" (submitted)
- "A gene index and gene expression atlas for gene discovery and characterization in switchgrass" (to be submitted)
- "Prokaryotic transcriptional unit identification using RNA-seq data" (to be submitted)
- "Clostridium thermocellum Transcriptional Architecture Improvement Using Systems Biology Data and Bioinformatics" (in preparation)
- (2011) D. Earl, K. Bradnam, J. St. John, A. Darling, D. Lin, J. Fass, H. On Ken Yu, V. Buffalo, D. R. Zerbino, M. Diekhans, N. Nguyen, P. Nuwantha, A. W.-K. Sung, Z. Ning, M. Haimel, J. T. Simpson, N. A. Fonseca, L. Birol, T. R. Docking, I. Y. Ho, D. S. Rokhsar, R. Chikhi, D. Lavenier, G. Chapuis, D. Naquin,N. Maillet, M. C. Schatz, D. R. Kelley, A. M. Phillippy, S. Koren, S.-P. Yang, W. Wu, W.-C. Chou, A. Srivastava, T. I. Shaw, J. G. Ruby, P. Skewes-Cox, M. Betegon, M. T. Dimon, V. Solovyev, I. Seledtsov, P. Kosarev, D. Vorobyev, R. RamirezGonzalez, R. Leggett, D. MacLean, F. Xia, R. Luo, Z. L, Y. Xie, B. Liu, S. Gnerre, I. MacCallum, D. Przybylski, F. J. Ribeiro, S. Yin, T. Sharpe, G. Hall, P. J. Kersey, R. Durbin, S. D. Jackman, J. A. Chapman, X. Huang, J. L. DeRisi, M. Caccamo, Y. Li, D. B. Jaffe, R. E. Green, D. Haussler, I. Korf, and B. Paten, "Assemblathon 1: A competitive assessment of de novo short read assembly methods", Genome Research. [link]
- (2010) P. Dam, I. Kataeva, S.-J. Yang, F. Zhou, Y. Yin, W.-C. Chou, F. L Poole, R. Hettich, R. Gianonne, J. Westpheling, D. L Lewis, R. M Kelly, H. J Gilbert, B. Henrissat, Y. Xu and M. W. W. Adams, "Insights into Plant Biomass to Biofuel Conversion from the Genome Sequence of the Extremely Thermophilic Bacterium Caldicellulosiruptor bescii DSM 6725", Nucleic Acids Research. [pubmed]
- (2010) J. Cui, Y. Chen, W.-C. Chou, L. Sun, L. Chen, J. Suo, Z. Ni, M. Zhang, X. Kong, L. L. Hoffman, J. Kang, X. Lv, Y. Su, Y. Gao, H. Zhang, V. Olman, G. Li, D. Johnson, D. W. Tench, I. J. Amster, R. Orlando, D. Puett, F. Li, and Y. Xu, "An integrated transcriptomic and computational analysis for biomarker identification in gastric cancer", Nucleic Acids Research. [pubmed]
- (2010) W.-C. Chou, Y. Yin, Y. Xu, "GolgiP: prediction of Golgi resident proteins", Bioinformatics. [pubmed] [GolgiP Website]
- (2009) F. Mao, F. Zhou, Y. Yin, W.-C. Chou, C. Zhou, H. Chen, and Y. Xu, "pDAWG: an Integrated Database for Plant Cell-Wall Genes", BioEnergy Research. [SpringerLink] [pDAWG Website]
- (2009) I. A. Kataeva, S.-J. Yang, P. Dam, F. L Poole II, Y. Yin, F. Zhou, W.-C. Chou, Y. Xu, L. Goodwin, D. R. Sims, J. C. Detter, L. J. Hauser, J. Westpheling and M. W. W. Adams, "Genome Sequence of the Anaerobic, Thermophilic and Cellulolytic Bacterium Anaerocellum thermophilum DSM 6725", Journal of Bacteriology. [pubmed]
- (2009) F. Mao, P. Dam, W.-C. Chou, V Olman, and Y. Xu, "DOOR: a database for prokaryotic operons", Nucleic Acids Research. [pubmed] [Google Scholar] [DOOR Website]
- (2007) T.-H. Tsai, W.-C. Chou, Y.-C. Lin, Y.-S. Su, C.-L. Sung, H.-J. Dai, I. T.-H. Yeh, W. Ku, T.-Y. Sung and W.-L. Hsu, "BIOSMILE: A semantic role labeling system for biomedical verbs using a maximum-entropy model", BMC Bioinformatics. [pubmed]
- (2006) T.-H. Tsai, S.-H. Wu, W.-C. Chou, Y.-C. Lin, D. He, T.-Y. Sung, and W.-L. Hsu, "Various Criteria in the Evaluation of Biomedical Named Entity Recognition", BMC Bioinformatics. [pubmed]
- (2006) T.-H. Tsai, W.-C. Chou, S.-H. Wu, T.-Y. Sung, J. Hsiang, and W.-L. Hsu, "Integrating Linguistic Knowledge into a Conditional Random Field Framework to Identify Biomedical Named Entities", Expert Systems with Applications. [ACM]
- (2007) R. T.-H. Tsai, H.-J. Dai, H.-C. Hung, R. T.-K. Lin, W.-C. Chou, Y.-S. Su, M.-Y. Day, and W.-L. Hsu, BESearch: A Supervised Learning Approach to Search for Molecular Event Participants, Proceedings of the IEEE International Conference on Information Reuse and Integration.
- (2006) W.-C. Chou, T.-H. Tsai, Y.-S. Su, W. Ku, T.-Y. Sung, and W.-L. Hsu, "A Semi-Automatic Method for Annotating a Biomedical Proposition Bank", ACL Workshop on Frontiers in Linguistically Annotated Corpora 2006. [Google Scholar]
- (2006) T.-H. Tsai, W.-C. Chou, Y.-C. Lin, W. Ku, Y.-S. Su, T.-Y. Sung, and W.-L. Hsu, "BIOSMILE: Adapting Semantic Role Labeling for Biomedical Verbs: An Exponential Model Coupled with Automatically Generated Template Features", Proceedings of BioNLP-2006.
- (2004) Y.-F. Lin, T.-H. Tsai, W.-C. Chou, K.-P. Wu, T.-Y. Sung, and W.-L. Hsu, "A Maximum Entropy Approach to Biomedical Named Entity Recognition", Proceedings of 4th ACM SIGKDD Workshop on Data Mining in Bioinformatics (BioKDD).
- (2004) Y.-F. Lin, W.-C. Chou, K.-P. Wu, T.-Y. Sung, W.-L. Hsu, "InfoMap: A Framework for Integrated Proteomic Knowledge Base", Proceedings of 3rd International Proteomics Conference (IPC04).
- (2004) W.-L. Hsu, J.-M. Chang, W.-C. Chou, J.-B. Chen, K.-P. Wu, T.-Y. Sung, C.-F. Chang, W.-J. Wu and T.-H. Huang, "An Iterative Relaxation Technique for the NMR Backbone Assignment Problem", Proceedings of IEEE Fourth Symposium on Bioinformatics and Bioengineering (BIBE2004).
Posters
- (2011) W.-C. Chou, H. Zhang, Y. Yin, and Y. Xu, "Bacterial genome sequence finishing with functional genome structure", Genome Informatics Meeting at CSHL.
- (2009) Y. Yin, W.-C. Chou, Y. Xu, "Phylogenetic sub-classification of CAZy families and application in identification of novel glycosyl hydrolases in the environmental metagenomes", BioEnergy Science Center 3rd retreat.
- (2009) W.-C. Chou, M. Bar-Peled, Y. Xu, "Computational Prediction of Golgi Resident Proteins in Arabidopsis thaliana", Genomics:GTL Awardee Workshop VII.
- (2009) W.-C. Chou, M. Bar-Peled, Y. Xu, "Computational Prediction of Golgi Resident Proteins in Arabidopsis thaliana", BioEnergy Science Center 2nd retreat.
- (2008) W.-C. Chou, P. Dam, M. Bar-Peled, Y. Xu, "Prediction of Golgi Proteins Based on Structural Domains and Functional Domains", 3rd Annual Computational and Systems Biology Symposium.
Courses taken
- Fall 2007
*BCMB8010: Advanced Biochemistry and Molecular Biology I
*BCMB8210: Computational Methods in Bioinformatics
STAT6310: Statistical Analysis I - Spring 2008
*BCMB8211: Advanced Methods for Biological Data Analyses
STAT8090: Statistical Analysis of Genetic Data - Summer 2008
Introductory Programming for Biologists - Fall 2008
*CSCI6490: Algorithms for Computational Biology
*STAT6630: Statistical Bioinformatics I
#STAT8330: Advanced Applications and Computing - Spring 2009
*GENE8940: Genome Analysis
*STAT6640: Statistical Bioinformatics II - Summer 2009
#STAT6230: Applied Regression Analysis - Fall 2009
STAT8060: Computing Techniques in Statistics I - Spring 2010
EHSC8800: Genome technologies (emphasized Next-Generation Sequencing Technologies)
BINF8990: Bioinformatics Colloquium
*: Ph.D. core course
#: Auditing