PRIME is a mass spectrum data mining tool for peptide de novo sequencing and protein post-translational modifications identification. At its early stage, PRIME 0.9 employs a graph-theoretic approach to separate b and y ions in a tandem mass spectrum. The version 1.0 will be coming soon.
PRIME 0.9 is implemented with C/C++. For free download,
Bo Yan, Chongle Pan, Victor N. Olman, Robert L. Hettich, and Ying Xu. A graph-theoretic approach for the separation of b and y ions in tandem mass spectra. Bioinformatics 21: 563-574, 2005.
B. Yan, Y. Qu, F. Mao, V Olman, Ying Xu, PRIME: A Mass Spectrum Data Mining Tool for De Novo Sequencing and PTMs Identification. Journal of Computer Science and Technology (in press), 2005.
Bo Yan, Chongle Pan, Victor N. Olman, Robert L. Hettich, and Ying Xu. Separation of ion types in tandem mass spectrometry data interpretation ¨C a graph-theoretic approach. Proceedings of The IEEE Computational Systems Bionformatics Conference (CSB'04), pp. 236 - 244, 2004.
Bo Yan | Chongle Pan | Victor Olman | Ying Xu