PRIME 0.9

PRIME is a mass spectrum data mining tool for peptide de novo sequencing and protein post-translational modifications identification. At its early stage, PRIME 0.9 employs a graph-theoretic approach to separate b and y ions in a tandem mass spectrum. The version 1.0 will be coming soon.

PRIME 0.9 is implemented with C/C++. For free download,

l README

Reference:

Bo Yan, Chongle Pan, Victor N. Olman, Robert L. Hettich, and
Ying Xu. A graph-theoretic approach for the separation of b and y ions in
tandem mass spectra. *Bioinformatics* 21: 563-574, 2005.

B. Yan, Y. Qu, F. Mao, V Olman, Ying Xu, PRIME: A Mass
Spectrum Data Mining Tool for De Novo Sequencing and PTMs Identification. *Journal of Computer Science and Technology* (in
press), 2005.

Bo Yan, Chongle Pan, Victor N. Olman, Robert L. Hettich, and Ying Xu. Separation of ion types in tandem
mass spectrometry data interpretation ¨C a graph-theoretic approach. *Proceedings of The IEEE
Computational Systems Bionformatics Conference* (CSB'04), pp. 236 - 244, 2004.

People Involved

Bo Yan | Chongle Pan | Victor Olman | Ying Xu